Managing Contrast Reactions

*This information should only serve as a guide, and is not intended to supersede individual departmental policy.

Click here to access the ACR® Manual on Contrast Media

ADULTS

Diphenhydramine 50 mg PO, IM, or IV

Epipen® Delivers 0.3 mg Epinephrine IM
Repeat every 5 min up to 3 doses PRN

Epinephrine IM – 1 mg/mL (1:1,000 solution): 0.3 mL
Repeat every 5 min up to 3 doses PRN

Epinephrine IV – 0.1 mg/mL (1:10,000 solution): 1 mL slowly (2-5 min)
Repeat to total of 10 mL PRN

Atropine –  0.6 – 1.0 mg slowly.
Can be repeated up to 0.04 mg/kg (2-3 mg in most adults)

Beta-agonist Inhaler 2 puffs (180 mcg)
Can be repeated up to 3 times

 

Management of Contrast Extravasation

  • Evaluate for neurovascular compromise. If present, consult plastic surgery
  • Elevate the affected body part
  • Apply cold compress for 20 min TID/QID
  • Instruct patient to return to hospital if they develop skin ulceration, blistering, altered sensation, increased swelling/pain

PEDIATRICS

*Use of this information implies acceptance of the Terms of Use*

References

  • ACR Committee on Drugs and Contrast Media. (2018). ACR Manual on Contrast Media. Version 10.3.
  • Coley B. (2018). Caffey’s Pediatric Diagnostic Imaging: 13th Edition.
  • https://reference.medscape.com
  • Dillman J, Trout A, Davenport M. Allergic-like Contrast Media Reaction Management in Children. Pediatric Radiology. 21 September 2018